Lab & Equipment Details
Research Labs
20,000 square feet
Fifty-eight 10 and 8 foot fume hoods
Separate analytical labs
Dedicated hydrogenation bay
Designed for synthetic chemistry
NMR
300 MHz Bruker
400 MHz Bruker
Multi-nuclear probe
Variable Temperature
User Walk-up
Mass Spectroscopy
Walk-up LC/MS spectrometers
GC/MS system
Purification
CombiFlash Rf systems
Preparative HPLC systems
Agilent 1100 HPLC units
Process Equipment
50L, 22L and 10L Reactors
Cooling to -78C
Dedicated Suite
Containment for high potency
Additional Analytical
Walk-up LC/MS spectrometers
FT/IR
Polarimeter
Scientific Services
We believe that your projects deserve outstanding chemists skilled in innovation and problem solving.
Medicinal Chemistry

We don’t just make molecules, we make the right ones. Medicinal chemists are the scientific artists who create new chemical entities. They have the ability to integrate multiple data sources such as synthetic methodology, toxicology, ADME, pharmacology, physico-chemical characteristics and deliver potential new drugs. We are a company of experienced medicinal chemists with each having an average of 15 years of drug discovery and development experience. We provide IP enabling medicinal chemistry expertise, problem solving skills & excellent communication.

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Custom Synthesis

Kalexsyn has become known in the industry for its ability to execute challenging syntheses including Class II, III, IV and V compounds.. Much of our custom synthesis work comes from clients who have used other CROs that have failed to deliver a synthetic target. Our success is due to our chemists' decades of experience. At Kalexsyn, we have experience in a broad array of chemistries, allowing us to take on your most challenging targets. We understand the impact of meeting timelines. We have a complete array of analytical equipment at Kalexsyn and all materials are fully characterized prior to shipping. The analytical data packages accompany all shipments.

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Stable Label Synthesis

With advances in mass spectrometry we’ve seen an increase in the requests for preparation of stable label compounds. Our chemists are experienced in the preparation of stable label compounds containing 2H, 13C, 15N, and/or 18O.  We can help to support your pre-clinical and clinical development.

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Process Development

Kalexsyn's process improvement and scale-up capabilities can typically prepare 50-500 gram of your target in our early API reaction suite. Our process improvement ideas are discussed with our clients and clear, concise timelines and goals are set.

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